Destructive arthropathy in chondrocalcinosis articularis.

Morphological study of articular cartilage in pyrophosphate arthropathy. (Chondrocalcinosis articularis or calcium pyrophosphate dihydrate crystal deposition diseases).

Chondrocalcinosis articularis Section L Clinical and radiological study.

During the past 7 years we have had the opportunity of studying 27 cases of a condition characterized by multiple calcification of hyaline and fibrous cartilage both of the joints and of the intervertebral disks.* We present in this paper a detailed nosographical analysis of this clinical entity which we have named articular chondrocalcinosis (AC). Up to 1955, when we saw our first cases, we fo...

Pyrophosphate arthropathy--recent clinical advances.

It is now 20 years since McCarty et al. identified calcium pyrophosphate dihydrate (CPPD) crystals in synovial fluid from patients with acute arthritis and radiological chondrocalcinosis.' CPPD crystals were subsequently shown to be inflammatory both in vivo and in vitro2 and their causal role in joint disease, reflected by the term 'CPPD crystal-induced synovitis', was readily accepted. Cadave...

Pseudogout, chondrocalcinosis and the early recognition of haemochromatosis.

Idiopathic haemochromatosis is a disorder which has a well-known association with chondrocalcinosis. We report arthritis associated with chondrocalcinosis as the first clinical manifestation of underlying haemochromatosis in two otherwise asymptomatic male patients. In one patient, pyrophosphate arthropathy presented with acute pseudogout. Better appreciation of this presentation will result in...

Pseudogout: timing of attacks and the cosmogeophysical environment.

OBJECTIVE To search for a time parallelism between lunar and solar rotation cycles and calendar dates of attacks of pseudogout--chondrocalcinosis articularis (pyrophosphate arthropathy). METHODS Seventy-four documented attacks with known calendar dates of onset recorded in 16 patients of one family cluster between 1955 and 1995 were examined in this study. Their daily frequencies during the g...